Which statement describes a NOT a side effect after two months of prednisone therapy?

• A. Decreased wound healing
• B. Weight loss
• C. Hypertension
• D. Moon face

Answer: (B)

Prolonged prednisone use tends to cause weight gain due to increased appetite and fluid retention, along with fat redistribution that leads to moon face. It can also raise blood pressure and slow wound healing because corticosteroids impair collagen synthesis and immune responses. Weight loss, in contrast, is not a typical effect after two months of therapy, so that statement describes what is not expected.